1-832-868-1888
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Catalog Number: |
42229 |
| other_names: | IFITM1 |
Amount: |
100μg |
| calculated_mw: | 14kd |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P13164 |
Form of Antibody: |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage/Stability: |
|
Immunogen: |
Recombinant human Interferon-induced transmembrane protein 1 protein |
Purification: |
Caprylic Acid Ammonium Sulfate Precipitation purified |
Specificity/Sensitivity: |
The antibody detects endogenous level of total Interferon-induced transmembrane protein 1 polyclonal antibody. |
Applications: |
WB |
Background: |
IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals. |
References: |
[1] "A single DNA response element can confer inducibility by both alpha- and gamma-interferons."Reid L.E., Brasnett A.H., Gilbert C.S., Porter A.C.G., Gewert D.R., Stark G.R., Kerr I.M.Proc. Natl. Acad. Sci. U.S.A. 86:840-844(1989) [2] "Expression clon |
appl_detail: |
Western blotting: 1:500 - 1:1000 |
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