Gastric intrinsic factor Polyclonal Antibody

Catalog Number:

42180

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P27352

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Gastric intrinsic factor protein£¨19-417aa£©

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Gastric intrinsic factor polyclonal antibody.

Applications:

IHC

Background:

Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis.

References:

[1]"Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene." Tanner S.M., Li Z., Perko J.D., Oener C., Cetin M., Altay C., Yurtsever Z., David K.L., Faivre L., Ismail E.A., Graesbeck R., de la Chapelle A. Proc. Natl. Aca

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF