Acetylcholine receptor subunit alpha Polyclonal Antibody

Catalog Number:

42123

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04756

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant mouse Acetylcholine receptor subunit alpha protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Acetylcholine receptor subunit alpha polyclonal antibody.

Applications:

WB

Background:

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

References:

[1]"Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution." Dellisanti C.D., Yao Y., Stroud J.C., Wang Z.Z., Chen L. Nat. Neurosci. 10:953-962(2007). [2]"The transcriptional landscape of the mamm

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF