H-2 class II histocompatibility antigen gamma chain Polyclonal Antibody

Catalog Number:

42111

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04441

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant mouse H-2 class II histocompatibility antigen gamma chain protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total H-2 class II histocompatibility antigen gamma chain polyclonal antibody.

Applications:

WB

Background:

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

References:

[1]"Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin."Koch N., Lauer W., Habicht

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF