CCL8 Polyclonal Antibody

Catalog Number:

42106

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P80075

Form of Antibody:

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

Recombinant human C-C motif chemokine 8 protein(23-99aa)

Purification:

Antigen Affinity Purified

Specificity/Sensitivity:

The antibody detects endogenous level of total CCL8 polyclonal antibody.

Applications:

IHC

Background:

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.

References:

[1]Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors."Blaszczyk J., Coillie E.V., Proost P., Damme J.V., Opdenakker G., Bujacz G.D., Wang J.M., Ji X. Biochemistry 39:14075-14081(2000). [2]P

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF