SUMO-conjugating enzyme UBC9 Polyclonal Antibody

Catalog Number:

42105

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P63279

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human SUMO-conjugating enzyme UBC9 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total SUMO-conjugating enzyme UBC9 polyclonal antibody.

Applications:

WB IHC

Background:

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation

References:

[1]"Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9."Yasugi T., Howley P.M.Nucleic Acids Res. 24:2005-2010(1996) [2]"Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human c

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF