Carbonic anhydrase 2 Polyclonal Antibody

Catalog Number:

42099

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P00918

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Carbonic anhydrase 2 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Carbonic anhydrase 2 polyclonal antibody.

Applications:

WB

Background:

Essential for bone resorption and osteoclast differentiation .Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.

References:

[1]"Carbonic anhydrase II deficiency syndrome (osteopetrosis with renal tubular acidosis and brain calcification): novel mutations in CA2 identified by direct sequencing expand the opportunity for genotype-phenotype correlation."Shah G.N., Bon

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF