Cytokeratin 18 Mouse Monoclonal Antibody (1B3)

Catalog Number:

38048

Amount:

100μg

Price:

$369

Swiss-Prot No:

Swiss-Prot#:P05783

Form of Antibody:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purification:

Affinity purification using immunogen.

Specificity/Sensitivity:

Antibody detects endogenous Cytokeratin 18 protein.

Applications:

WB,IF

Background:

Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

References:

appl_detail:

WB dilution: 1:1000~1:3000

IF dilution:1:200

Datasheet PDF