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CDX2 Mouse Monoclonal Antibody

Catalog Number:

38012
other_names: caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2

Amount:

100μg
calculated_mw:
host_species: Mouse

Price:

$369

Swiss-Prot No:

Swiss-Prot#:Q99626

Form of Antibody:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purification:

Affinity purification using immunogen.

Specificity/Sensitivity:

The CDX2 Mouse Monoclonal antibody detects endogenous CDX2 proteins.

Applications:

WB,IHC,IF

Background:

CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.

References:

appl_detail:

WB dilution: 1:1000~1:2000
IHC dilution: 1:200

IF dilution:1:200

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