EGFR Mouse Monoclonal Antibody

Catalog Number:

37996

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:P00533

Form of Antibody:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purification:

Affinity purification using immunogen.

Specificity/Sensitivity:

The EGFR Mouse Monoclonal antibody detects endogenous EGFR proteins.

Applications:

WB,IHC,IF

Background:

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.

References:

appl_detail:

WB dilution: 1:1000

IF dilution:1:100-200

Datasheet PDF