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hHR23b Monoclonal Antibody

Catalog Number:

27219
other_names: homolog of B; RAD23B; RD23B_HUMAN; UV excision repair protein RAD23 homolog B; XP C repair complementing complex 58 kDa; XP C repair complementing complex 58 kDa protein; XP C repair complementing protein; XP-C repair-complementing complex 58 kDa protein;

Amount:

100μg
calculated_mw:
host_species: Mouse

Price:

$369

Swiss-Prot No:

Uniprot: P54727

Gene ID: 5887

Form of Antibody:

Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purified recombinant human hHR23b protein fragments expressed in E.coli.

Purification:

Affinity purified

Specificity/Sensitivity:

This antibody detects endogenous levels of hHR23b and does not cross-react with related proteins.

Applications:

WB ICC IHC

Background:

Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
 

References:

appl_detail:

Western blotting: 1:1000

Immunocytochemistry: 1:100

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