Placental alkaline phosphatase (PLAP) Monoclonal Antibody

Catalog Number:

27192

Amount:

100μg

Price:

$369

Swiss-Prot No:

Uniprot: P05187

Gene ID: 250

Form of Antibody:

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.2% sodium azide, 50% glycerol, 0.1%BSA

Storage/Stability:

Immunogen:

Purified recombinant human ALPP protein fragments expressed in E.coli.

Purification:

Affinity purified

Specificity/Sensitivity:

This antibody detects endogenous levels of ALPP and does not cross-react with related proteins.

Applications:

WB ICC

Background:

 There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

References:

appl_detail:

Western blotting: 1:500

Immunocytochemistry: 1:300

Datasheet PDF