CBR1 Monoclonal Antibody

Catalog Number:	27187
other_names:	15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
Amount:	100μg
calculated_mw:
host_species:	Mouse
Price:	$369
Swiss-Prot No:	Uniprot: P16152 Gene ID: 873
Form of Antibody:	Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.
Storage/Stability:
Immunogen:	Purified recombinant human CBR1 protein fragments expressed in E.coli
Purification:	Affinity purified
Specificity/Sensitivity:	This antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.
Applications:	WB ICC
Background:	NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
References:
appl_detail:	Western blotting: 1:1000 Immunocytochemistry: 1:100
	Datasheet PDF

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