Mouse anti-Human CD56, PE Conjugated mAb

Catalog Number:

28177

Amount:

100μg

Price:

$529

Swiss-Prot No:

Form of Antibody:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Storage/Stability:

Immunogen:

Purification:

Specificity/Sensitivity:

Applications:

FC

Background:

 COC56 reacts with CD56, a 175-220 kDa Neural Cell Adhesion Molecule (NCAM), expressed on 10-25% of peripheral blood lymphocytes, including all CD16+ NK cells and approximately 5% of CD3+ lymphocytes, referred to as NKT cells. It also is present at brain and neuromuscular junctions, certain LGL leukemias, small cell lung carcinomas, neuronally derived tumors, myeloma and myeloid leukemias. CD56 (NCAM) is involved in neuronal homotypic cell adhesion which is implicated in neural development, and in cell differentiation during embryogenesis.

 

1. Knapp, W et al., eds. (1989) Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.

2. Lanier LL . et al. (1991)  J. Immunol. 146:4421-4426.

3. Campbell, JJ et al. (2001) J. Immunol . 166:6477-6482.

4. Cooper MD  et al. (2001)  Trends in Immunol. 22:633-640.

5. Galandrini R  et al. (2002)  Blood. 100:4581-4589.

References:

appl_detail:

Vol.per.Test: 10 μl/Test

Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

Datasheet PDF