Mouse anti-Human CD45, PE Conjugated mAb

Catalog Number:

28143

Amount:

100μg

Price:

$529

Swiss-Prot No:

Form of Antibody:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Storage/Stability:

Immunogen:

Purification:

Specificity/Sensitivity:

Applications:

FC

Background:

 4AA9 reacts with CD45, a 180-220 kDa leukocyte common antigen (LCA). CD45 antigen is expressed at high levels on all hematopoietic cells including T and B lymphocytes, monocytes, granulocytes, NK cells and dendritic cells, but is not expressed on non-hematopoietic cells. CD45 antibody has also been reported to react weakly with mature blood erythrocytes and platelets. CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated activation.

*Target of immunosuppresive antibody treatment.

 

1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.

2. Trowbridge, IS and Thomas, ML. (1993) Annu. Rev. Immunol. 12:85.

3. Pulido, R et al., (1988) J. Immunol.  140:3851.

4. Roach, T et al., (1997) Curr. Biol. 7:408.

References:

appl_detail:

Vol.per.Test: 10 μl/Test

Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

Datasheet PDF