Mouse anti-Human CD19, Purified mAb

Catalog Number:

28071

Amount:

100μg

Price:

$529

Swiss-Prot No:

Form of Antibody:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide

Storage/Stability:

Immunogen:

Purification:

Specificity/Sensitivity:

Applications:

FC

Background:

 COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.

* CD19 is a key phenotyping marker of non-T cell leukemia.

 

1.  Nadler, LM et al. (1983) J. Immunol. 131:244

2. Schlossman, SL et al., eds. (1995)  Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York.

3.  Tedder T. et al.  (1994)  Immunol Today. 15:437-442

References:

appl_detail:

Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

Datasheet PDF