Mouse anti-Human CD16, PE Conjugated mAb

Catalog Number:

28064

Amount:

100μg

Price:

$529

Swiss-Prot No:

Form of Antibody:

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Storage/Stability:

Immunogen:

Purification:

Specificity/Sensitivity:

Applications:

FC

Background:

 COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.

This clone is cross reactive with non-human primate.

 

1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.

2. Stroncek, D.F., et al. (1991) Blood 77:1572.

3. Wirthmueller, U., et al.  (1992) J. Exp. Med. 175:1381.

4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

References:

appl_detail:

Vol.per.Test: 10 μl/Test

Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

Datasheet PDF