PRELP antibody

Catalog Number:

40410

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q69YG0
NCBI Protein#: BC032498

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human PRELP

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

WB, IHC

Background:

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB dilution:1:500-1:2000
IHC dilution:1:100-1:300

Datasheet PDF