TOP2B Antibody

Catalog Number:

40387

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q02880
Gene Accssion:NP_001059

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human topoisomerase (DNA) II beta 180kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TOP2B protein.

Applications:

WB

Background:

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA.?

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF