SULF1 Antibody

Catalog Number:

40377

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8IWU6
Gene Accssion:NP_055985

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human sulfatase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SULF1 protein.

Applications:

IHC

Background:

This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry:1:10-1:50

Datasheet PDF