TPR Antibody

Catalog Number:

40365

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P12270
Gene Accssion:NP_003283

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human translocated promoter region, nuclear basket protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TPR protein.

Applications:

IHC

Background:

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF