SHANK1 Antibody

Catalog Number:

40359

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y566
Gene Accssion:NP_057232

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SH3 and multiple ankyrin repeat domains 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SHANK1 protein.

Applications:

WB

Background:

SHANK1 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF