KIT Antibody

Catalog Number:

40357

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P10721
Gene Accssion:NP_000213

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KIT protein.

Applications:

IHC

Background:

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF