UACA Antibody

Catalog Number:

40351

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9BZF9
Gene Accssion:BC113407

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human uveal autoantigen with coiled-coil domains and ankyrin repeats

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total UACA protein.

Applications:

IHC

Background:

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

References:

appl_detail:

Immunohistochemistry:1:30-1:150

Datasheet PDF