OLFM3 Antibody

Catalog Number:

40315

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96PB7
Gene Accssion:BC022531

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human olfactomedin 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OLFM3 protein.

Applications:

WB

Background:

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF