UTS2B Antibody

Catalog Number:

40287

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q765I0
Gene Accssion:NP_937795

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human urotensin 2B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total UTS2B protein.

Applications:

WB IHC

Background:

Potent vasoconstrictor.Human Urotensin II is composed of only 11 amino acid residues, while fish and frog Urotensin II possess 12 and 13 amino acid residues, respectively (2).?Human Urotensin II is found within both vascular and cardiac tissue, including coronary atheroma, and effectively constricts isolated arteries from nonhuman primates (3). Urotensin II may act as an autocrine and/or paracrine hormone rather than as a circulating hormone, by playing an important role in the development of ventricular hypertrophy induced by chronic hypoxia (4).

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200

Datasheet PDF