TRPM6 Antibody

Catalog Number:

40267

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9BX84
Gene Accssion:NP_060132

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human transient receptor potential cation channel, subfamily M, member 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRPM6 protein.

Applications:

WB

Background:

This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF