TNFRSF4 Antibody

Catalog Number:

40256

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P43489
Gene Accssion:NP_003318

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human tumor necrosis factor receptor superfamily, member 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNFRSF4 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF