VMP1 Antibody

Catalog Number:

40253

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96GC9
Gene Accssion:NP_112200

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human vacuole membrane protein 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VMP1 protein.

Applications:

IHC

Background:

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.?

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF