ERVW-1 Antibody

Catalog Number:

40230

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UQF0
Gene Accssion:NP_055405

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human endogenous retrovirus group W, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ERVW-1 protein.

Applications:

IHC

Background:

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta.?

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF