LLGL2 Antibody

Catalog Number:

40198

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6P1M3
Gene Accssion:NP_001015002

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human lethal giant larvae homolog 2 (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LLGL2 protein.

Applications:

IHC

Background:

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF