HCN4 Antibody

Catalog Number:

40181

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y3Q4
Gene Accssion:NP_005468

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human hyperpolarization activated cyclic nucleotide gated potassium channel 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HCN4 protein.

Applications:

IHC

Background:

This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.

References:

appl_detail:

Immunohistochemistry:1:10-1:50

Datasheet PDF