GZMK Antibody

Catalog Number:

40180

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P49863
Gene Accssion:NP_002095

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human granzyme K (granzyme 3; tryptase II)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GZMK protein.

Applications:

IHC

Background:

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF