THAP6 Antibody

Catalog Number:

40143

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8TBB0
Gene Accssion:BC022989

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total THAP6 protein.

Applications:

IHC

Background:

THAP6 (THAP domain-containing protein 6) is a 222 amino acid protein that contains one THAP-type zinc finger and exists as two alternatively spliced isoforms. The gene that encodes THAP6 consists of approximately 36,528 bases and maps to human chromosome 4q21.1. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF