STXBP4 Antibody

Catalog Number:

40130

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q08AL9
Gene Accssion:BC125116

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human syntaxin binding protein 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STXBP4 protein.

Applications:

IHC

Background:

Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF