SNX15 Antibody

Catalog Number:

40112

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NRS6
Gene Accssion:BC012767

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SNX15 protein.

Applications:

IHC

Background:

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors.

References:

appl_detail:

Immunohistochemistry:1:20-1:100

Datasheet PDF