SCAP Antibody

Catalog Number:

40093

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q12770
Gene Accssion:BC020987

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human SREBF chaperone

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCAP protein.

Applications:

IHC

Background:

This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF