ATOX1 Antibody

Catalog Number:

40087

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O00244
Gene Accssion:BC112248

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATOX1 protein.

Applications:

IHC

Background:

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF