RASSF7 Antibody

Catalog Number:

40072

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q02833
Gene Accssion:BC106921

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RASSF7 protein.

Applications:

WB IHC

Background:

RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:200

Datasheet PDF