PTPMT1 Antibody

Catalog Number:

40065

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8WUK0
Gene Accssion:BC020242

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human protein tyrosine phosphatase, mitochondrial 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTPMT1 protein.

Applications:

WB

Background:

PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic cells. PTPMT1 exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF