TAF10 Antibody

Catalog Number:

40234

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q12962
Gene Accssion:NP_006275

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TAF10 protein.

Applications:

WB IHC

Background:

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:25-1:100

Datasheet PDF