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BARK1 Monoclonal Antibody

Catalog Number:

27101
other_names: GRK2, BARK1, BETA-ARK1

Amount:

100μg
calculated_mw:
host_species: Mouse

Price:

$369

Swiss-Prot No:

Swiss-Prot:P13639
Gene ID:1938

Form of Antibody:

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Storage/Stability:

Immunogen:

Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.

Purification:

Affinity purified

Specificity/Sensitivity:

Applications:

ELISA WB

Background:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.

References:

appl_detail:

Predicted MW: 80kd
Western blotting: 1:1000

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