PCBD1 antibody

Catalog Number:

38872

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P61457
NCBI Gene ID: 5092

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human PCBD1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total PCBD1 antibody.

Applications:

WB,IF

Background:

This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:10 - 1:100

Datasheet PDF