ZC3HC1 antibody

Catalog Number:

38830

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q86WB0
NCBI Gene ID: 51530

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human ZC3HC1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total ZC3HC1 antibody.

Applications:

WB

Background:

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF