ERCC6L antibody

Catalog Number:

38729

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q2NKX8
NCBI Gene ID: 54821

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human ERCC6L.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total ERCC6L antibody.

Applications:

WB

Background:

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF