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Catalog Number: |
38582 |
| other_names: | NFAT1; NFATP |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q13469 |
Form of Antibody: |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
A synthetic peptide of human NFATC2. |
Purification: |
Antibodies were purified by affinity purification using immunogen. |
Specificity/Sensitivity: |
The antibody detects endogenous level of total NFATC2 antibody. |
Applications: |
WB |
Background: |
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
References: |
|
appl_detail: |
WB 1:500 - 1:1000 |
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