SUMO4 antibody

Catalog Number:

38579

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6EEV6
NCBI Gene ID: 387082

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthetic peptide of human SUMO4.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total SUMO4 antibody.

Applications:

WB,IHC

Background:

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

References:

appl_detail:

WB 1:1000 - 1:2000
IHC 1:100 - 1:300

Datasheet PDF