GEMIN2 antibody

Catalog Number:

38570

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14893
NCBI Gene ID: 8487

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthetic peptide of human GEMIN2.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total GEMIN2 antibody.

Applications:

WB,IHC,IF

Background:

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

References:

appl_detail:

WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Datasheet PDF