DRD4 antibody

Catalog Number:

38483

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P21917
NCBI Gene ID: 1815

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthetic peptide of human DRD4.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total DRD4 antibody.

Applications:

WB IHC

Background:

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

References:

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:50 - 1:100

Datasheet PDF