SKI antibody

Catalog Number:

38475

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P12755
NCBI Gene ID: 6497

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthetic peptide of human SKI.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total SKI antibody.

Applications:

WB

Background:

The Ski protein is a nuclear protooncoprotein that is associated with tumors at high cellular concentrations.It has been shown to interfere with normal cellular functioning by both directly impeding expression of certain genes inside the nucleus of the cell and disrupting signaling proteins that activate genes.This protein may play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. May functions in TGF-beta signaling.

References:

appl_detail:

WB 1:500 - 1:1000

Datasheet PDF